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Enclomiphene citrate may be the trans isomer of clomiphene citrate and functions being a non-steroidal estrogen receptor antagonist.

Enclomiphene citrate is mostly currently being investigated utilised to deal with male subjects with chronically minimal testosterone amounts due to secondary hypogonadism. In this particular issue, minimal testosterone amounts are as a result of dysfunction within the hypothalamic pituitary gonadal (HPG) axis.

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Enclomiphene citrate has long been the topic of diverse medical scientific studies, notably focusing on its ability to elevate serum testosterone degrees even though preserving regular sperm counts in male topics with secondary hypogonadism.